When discussing male infertility, the focus is often on the most common causes. However, it is important to consider that certain abnormalities may be linked to other underlying conditions or diseases, which can potentially give rise to additional complications. Early detection of these issues offers the opportunity for correction or exploration of more effective alternative solutions.
Oligospermy is a common and significant condition that can hinder male fertility by reducing the quantity of sperm in the semen. According to data provided by the World Health Organization (WHO), a man is diagnosed with oligospermy when his sperm concentration is below 15 million spermatozoa per milliliter.
Oligospermy can be attributed to various factors, including hormonal disorders, testicular issues, or infections. Besides, it is often associated with other conditions, some of which are described below:
Cryptorchidism: a condition associated with oligospermy
Cryptorchidism refers to the condition wherein one or both testicles fail to descend into the scrotum before birth. This can give rise to fertility difficulties because the undescended testicles are exposed to elevated temperatures, which can impact the production of sperm.
Cryptorchidism primarily occurs in a single testicle, accounting for approximately 80% of cases, and the left testicle is more commonly affected. Bilateral cryptorchidism, where both testicles are altered, is less common. To prevent fertility challenges, it is recommended that boys with cryptorchidism undergo surgery to descend the testicles into the scrotum before the age of 2 years.
Varicocele
Testicular varicocele is a condition that causes dilation of the veins supplying the testicles. This can cause an elevation of testicular temperature, which can impact sperm production. It is most common in one testicle, but can also influence both. If it influences both testicles, it is more likely to cause infertility.
Additionally, testicular varicocele can lead to a condition called oligoasthenoteratozoospermia, which is characterized by low-quality spermatozoa in terms of both quantity and quality, including motility and morphology.
Adequate treatment can lead to notable improvement in cases of oligoasthenoteratozoospermia associated with testicular varicocele. Surgery is generally considered the most effective treatment, particularly in severe instances.
Hypogonadism and oligospermy: links in reproductive health
Male hypogonadism refers to the condition in which the testicles do not produce an adequate amount of sex hormones, including testosterone. This hormonal imbalance significantly affects sperm production and can lead to infertility.
There are two primary types of male hypogonadism that can be distinguished:
- Primary hypogonadism occurs when the testes are unable to function properly due to internal issues. A well-known genetic disorder associated with this type is Klinefelter’s syndrome, which often leads to low testosterone levels, diminished muscle mass, limited facial and body hair growth, and decreased sperm production.
- Secondary hypogonadism occurs when there is a problem in the hypothalamus or pituitary glands, which are responsible for producing the hormones that stimulate sperm production in the testes.
The treatment approach for hypogonadism varies depending on the type of the condition. In certain cases, hormonal treatment can be employed to restore testicular function and enhance sperm production, thereby increasing the chances of improved fertility.
Hydrocele
Testicular hydrocele is a condition characterized by the accumulation of fluid around one or both testicles. It can be either congenital or acquired, and it is more frequently observed in men who are over 40 years old.
Hydrocele is not a direct cause of infertility, but may be associated in 10% of cases, in which it can cause a partial obstruction of the vas deferens, which can reduce the number of sperm in the semen.
Oligoasthenoteratozoospermia
Oligotherotherozoospermia is a condition in which the concentration of spermatozoa in the semen is low and the shape of the spermatozoa is abnormal. This term brings together two spermogram findings, “Oligo” which refers to a low sperm concentration (less than 15 million x ML), and “terato” refers to a low concentration of normal shaped sperm (less than 4%). Abnormalities in sperm shape hinder fertilization and may also affect embryo development.
In cases of severe oligoteratozoospermia, men who wish to have children often undergo in vitro fertilization (IVF) treatment with intracytoplasmic sperm injection (ICSI). During this procedure, sperm with normal morphology are carefully chosen under microscopic guidance and directly injected into the egg. By employing this method, the chances of obtaining a viable embryo are significantly increased.
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While receiving any of these diagnoses may initially dishearten men in their pursuit of starting a family, it is crucial to acknowledge the positive aspect of identifying these conditions early for timely treatment. This recognition can serve as a pivotal moment in improving fertility and overall well-being.
It is recommended to maintain regular general check-ups to not only enhance the likelihood of starting a family but also to prevent the occurrence of these diagnoses, which can have irreversible consequences. These conditions have the potential to impact the health and well-being of individuals.
If you are aspiring to start a family but are encountering difficulties in conception or are aware of someone facing infertility or related complications, it is essential to reach out to specialized clinics that specialize in oligospermy, male fertility, and assisted reproduction, such as Babynova Clinic by Novafem. Seeking advice and treatment from these clinics at the earliest opportunity can make a significant difference in addressing these issues.